Revival Of Heart Cells Using Stem Cell Therapy
In recent times, stem cell treatments have opened up a broad spectrum for many health conditions, especially for genetic disorders, immunodeficiency disorders, and spinal cord injuries and not to mention- the heart disease.
When we talk about the complications involved with cardiovascular disease, it makes sense to find out more about how stem cells are effective in the treatment of this disorder.
The Normal Heart Cells And Its Normal Function
Our heart is capable of renewing its cells from as early as our fetus stage. During this time, the heart grows by increasing their cells. We can see a steady growth of heart cells as we grow up. There is generally no change and decrease in the total number of heart cells in a healthy and uninjured adult human heart.
According to the studies, the renewal capacity of heart cells has already been inherent in the heart from its fetus phase. This modest level of heart cell growth proliferates with the times but slows down when injured or goes under basal conditions.
In addition, our heart tends to grow its cells at every stage like adolescence, middle age and old age. Once reaching 50, we retain 55 percent of heart cells from our birth, while 45 percent of cells develop later in life.
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The growth of new heart cells following an injury
Do you believe the possibility of heart’s revival at a fast pace following an injury? In most cases, the rate of new cell growth to the injured heart is higher as compared to the heart remaining at a normal condition. It is not that you have to believe only those said words of some individuals. The statements have a validation of different research and studies, which focuses on its revival at steady speed after an injury. All this is possible due to the different therapies involving infusions, injections, and various cells derived implants like stem cell therapies. They prove beneficial for the injured hearts. The transplanted cells are effective in regenerating or renewing the injured heart cells in compliance with the existing heart cells. In addition, the new growth of heart cells in injured tissues in the cardiovascular structure is solely dependent on various sources of cells as well as their capacities.
Let us remove the veil from it and have it in a more clear way. As soon as the new heart cells are injected using bone marrow-derived stem cells, the retention remains at a low degree. However, the bone marrow-derived stem cells infused with CD43 proteins on their surfaces, become more effective for the renewal of new heart cells as their retention increases about tenfold. This protein takes a key role in migrating new stem cells into the heart muscles at a fast pace.
Disagreement about Stem Cells’ Effectiveness
Though the renewal of new heart cells or proliferation is possible with transfusions and stem cell transplant, the functional improvement of the newly transplanted stem cells into the heart is rarely achievable. And hence, researchers are finding other ways to make the whole process of renewal of new heart cells workable for the patients. Therefore, they believe that the heart cells from early stem cells can be beneficial to regenerate new heart cells and contribute to blood pumping functions as well as the heartbeat in sync with the pre-existing heart muscle.
Successful Clinical Trials
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While there is a disagreement regarding the role of stem cell transplant in promoting an effective cardiac function, a large number of successful clinical trials can prove their usefulness. These trials can prove promising for us as they can bring the real and effective results of stem cell transplant to be used on humans from the lab setting with an approval.
While there is a disagreement regarding the role of stem cell transplant in promoting an effective cardiac function, a large number of successful clinical trials can prove their usefulness. These trials can prove promising for us as they can bring the real and effective results of stem cell transplant to be used on humans from the lab setting with an approval.
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